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MRL lpr Mice

《英文msh詞典》MRL lpr Mice
[入口詞] MRL lpr Mice
[主題詞] Mice,Inbred MRL lpr
[英文釋義] A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome,which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also,the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.